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4 Mode of delivery of NDBs for antibacterial treatment Based on R&D reports, the most common local modes of delivery of antibacterial naturally derived biopolymers (aNDBs) to treat desired sites for various biomedical applications are summarized in Figure 3

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Central among them is upregulation and functional activation of vascular endothelial growth factor receptor 2 (VEGFR2), which underlies the molecule’s well-documented pro-angiogenic activity in endothelial cell cultures and in-vivo vasculogenesis assays (Hsieh et al., 2017)