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The nanoformulation exhibited good anticancer performance, and a synergistic antitumor effect against the human osteosarcoma cell lines, including Saos-2 and MG-63, likely due to down-regulation of X-linked inhibitor of apoptosis (XIAP), survivin, and human telomerase catalytic subunit (hTERT) ( p 3 logarithmic units, while in Escherichia coli it showed a bacteriostatic effect, reducing the number of viable cells 50% of tumor cells and exhibited a synergistic effect on the anti-tumor activity of CUR

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10.1111/j.1440-1797.2012.01642.x 31