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Thymoquinone can increase the expression of mitochondrial ROS scavenging enzymes and antioxidant molecules, such as GPX, catalase, SOD and GSH, and restore renal mitochondrial viability via Nrf2 in various kidney diseases models (Hannan et al., 2021
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Am J Physiol Lung Cell Mol Physiol 283:L707–L716 [DOI] [PubMed] [Google Scholar] McCoy AT, Benoist CC, Wright JW, Kawas LH, Bule-Ghogare JM, Zhu M, Appleyard SM, Wayman GA, Harding JW