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Met66 homozygous knock-in mice showed a selective impairment in activity-dependent synaptic plasticity in vitro (Ninan et al., 2010)

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Toxins interfere with proper thyroid function, as explained in the Environmental Protection Agency’s (EPA’s) article, “What is Endocrine Disruption?” The effects of endocrine (including thyroid) disruption include: Developmental malformations Interference with reproduction Increased cancer risk Disturbances in the immune and nervous system function These disruptions are caused by a number of manufactured and naturally occurring chemicals, including organochlorine compounds, ethane (DDT) and its metabolite DDE, and polychlorinated biphenyls (PCBs)