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Definition As per a universal definition proposed in 2021, “HF is a clinical syndrome with symptoms and/or signs caused by a structural and/or functional cardiac abnormality and corroborated by elevated natriuretic peptide levels and/or objective evidence of pulmonary or systemic congestion.” [] HF is diagnosed based on clinical features and supported by an elevation of natriuretic peptides in the blood (more than 125 pg/mL of N-terminal pro-b-type natriuretic peptide in ambulatory patients and more than 300 pg/mL in decompensated or hospitalized patients)