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Monday + Thursday) Total per week: 4–5 mg Aggressive loading (severe / acute injuries): 5 mg per injection , twice weekly = 10 mg/week Conservative loading (prevention / budget): 2.5 mg per injection , twice weekly = 5 mg/week Duration: 4–6 weeks Total peptide for standard loading: approximately 40–50 mg (standard) or 80 mg (aggressive) TB-500 maintenance phase dosage Standard maintenance dose: 2–2.5 mg once weekly Reduced maintenance: 2 mg every 2 weeks (for long-term joint support) Duration: 4–8 weeks after loading