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The results showed that WT-Bcr-Abl cells were highly susceptible to JMF4073 with GI 50 0.67 μM as compared to 1.5 μM and 4.2 μM for T315I-Bcr-Abl-32D and untransformed 32D cells, respectively (Fig

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Crystallization and X-ray diffraction data collection The crystallization and preliminary X-ray diffraction data analysis of the apo-OsDHAR were performed as described previously 30