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In a randomized Phase II study in patients undergoing liver transplantation, 30 mg/kg NAC administered 1 h before liver procurement and 150 mg/kg via portal vein in the recipient before liver implantation improved transplant survival by about 20% after one year and limited the risk of primary non-function

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Pharmacokinetics: Sarin is the most volatile of the nerve agents , which means that it can easily and quickly evaporate from a liquid into a vapor and spread into the environment People can be exposed to the vapor even if they do not come in contact with the liquid form of sarin Sarin's elimination half life estimated from studies with rats was estimated to be 3.7 hrs (Shih et al, 1994)