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Common issues include gastrointestinal (GI) discomfort, such as nausea, vomiting, diarrhea, and constipation, especially in GLP-1 receptor agonists like semaglutide and liraglutide

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Some differences regarding which allele confers risk may be attributable to comparisons among studies of different cancers, and may reflect underlying differences in carcinogenic mechanisms and tissue-specific expression of other modifying factors, including other GPxs