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(19) Older research taken from the National Health and Nutrition Examination Surveys (NHANES) also linked low B12 levels to shorter sleep duration than normal (up to six hours a night)

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Nonetheless, with the exception of certain viral encephalitis and prion disorders [499], such conditions are not fundamentally enigmatic and are less central to current neurodegeneration-focused drug development efforts compared to diseases like AD or frontotemporal lobar degeneration